Facial deformation in womb

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Click here to view a larger image. The lip forms between the fourth and seventh weeks of pregnancy. As a baby develops during pregnancy, body tissue and special cells from each side of the head grow toward the center of the face and join together to make the face. This joining of tissue forms the facial features, like the lips and mouth. A cleft lip happens if the tissue that makes up the lip does not join completely before birth.
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Pediatric Saethre-Chotzen Syndrome

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Why we don't know what causes most birth defects

Even at the early stages of gestation, the fetal face can be examined. There have been observations of the normal anatomy, such as orbits and the forehead, starting with the 12th week of gestation. However, nowadays, ultrasound equipment still cannot distinguish the soft tissues of the face, which are too thin. Recently, three-dimensional ultrasound 3D images of the fetus can also be obtained. However, two-dimensional 2D ultrasonographic US images are more easily, rapidly, efficiently, and accurately obtained.
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Birth Defects

The development of a baby, from the time of fertilisation through to the moment of birth, is an incredibly complex journey. Most of the time the result is a perfect new baby. This is when an anatomical difference has come about as the baby develops in the womb.
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While still in the womb, some babies have problems with how their organs and body parts form, how they work, or how their bodies turn food into energy. These health problems are called birth defects. There are more than 4, different kinds of birth defects, ranging from minor ones that need no treatment to serious ones that cause disabilities or require medical or surgical treatment. If a baby is born with a part of the body that is missing or malformed, it is called a structural birth defect.
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